05710158 is referenced by 144 patents and cites 18 patents.

This invention relates to the modulation and/or inhibition of cell signaling, cell proliferation, cell inflammatory response, the control of abnormal cell growth and cell reproduction. More specifically, this invention relates to the use of mono- and/or bicyclic aryl or heteroaryl quinazoline compounds in inhibiting cell proliferation, including compounds which are useful protein tyrosine kinase (PTK) inhibitors. The method of treating cell proliferation using said quinazoline compounds and their use in pharmaceutical compositions is described.

Title
Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
Application Number
698420
Publication Number
5710158
Application Date
April 19, 1994
Publication Date
January 20, 1998
Inventor
Paul E Persons
King of Prussia
PA, US
Martin P Maguire
Mont Clare
PA, US
Alfred P Spada
Lansdale
PA, US
Michael R Myers
Reading
PA, US
Agent
Martin F Savitzky
James A Nicholson
Raymond S Parker III
Assignee
Rhone Poulenc Rorer Pharmaceuticals
PA, US
IPC
C07D 239/94
C07D 239/93
C07D 239/88
A61K 31/505
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