05688787 is referenced by 39 patents and cites 13 patents.

Novel compounds of the formula ##STR1## wherein A is --CH.dbd.CH--B; --C.tbd.C--B; --(CH.sub.2).sub.p --X--B, and X is a bone, --NH-- or --S(O).sub.0-2 --; optionally substituted heteroaryl or benzofused heteroaryl; --C(O)--B; or ##STR2## D is B'--(CH.sub.2).sub.m C(O)--, B'--(CH.sub.2).sub.q --, B'--(CH.sub.2).sub.e --Z--(CH.sub.2).sub.r, wherein Z is --O--, --C(O)--, phenylene, --NR.sub.8 -- or --S(O).sub.0-2 --, B'--(alkenylene)--; B'--(alkadienylene)--; B'--(CH.sub.2).sub.t --Z--(alkenylene), B'--(CH.sub.2).sub.f --V--(CH.sub.2).sub.g --, wherein V is cycloalkylene, B'--(CH.sub.2).sub.t --V--(alkenylene) or B'--(alkenylene)--V--(CH.sub.2).sub.t --, B'--(CH.sub.2).sub.a --Z--(CH.sub.2).sub.b --V--(CH.sub.2).sub.d --, T--(CH.sub.2).sub.s --, wherein T is cycloalkyl; naphthylmethyl or optionally substituted heteroarylmethyl;

Title
Substituted .beta.-lactam compounds useful as hypochlesterolemic agents and processes for the preparation thereof
Application Number
734652
Publication Number
5688787
Application Date
January 19, 1996
Publication Date
November 18, 1997
Inventor
Wayne Vaccaro
Princeton
NJ, US
Sundeep Dugar
Parlin
NJ, US
John W Clader
Cranford
NJ, US
Duane A Burnett
Fanwood
NJ, US
Agent
Eric S Dicker
Anita W Magatti
Assignee
Schering Corporation
NJ, US
IPC
C07D 401/04
C07D 403/10
C07D 205/08
A61K 31/395
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