05681575 is referenced by 102 patents and cites 102 patents.

Anti-microbial coatings and method of forming same on medical devices are provided. The coatings are formed by depositing a biocompatible metal by vapor deposition techniques to produce atomic disorder in the coating such that a sustained release of metal ions sufficient to produce an anti-microbial effect is achieved. Preferred deposition conditions to achieve atomic disorder include a lower than normal substrate temperature, and one or more of a higher than normal working gas pressure and a lower than normal angle of incidence of coating flux. Anti-microbial powders formed by mechanical working to produce atomic disorder are also provided. The invention extends to other metal coatings and powders similarly formed so as to provide enhanced solubility.

Title
Anti-microbial coating for medical devices
Application Number
885758
Publication Number
5681575
Application Date
May 7, 1993
Publication Date
October 28, 1997
Inventor
Larry Roy Morris
Edmonton
CA
Robert Edward Burrell
Sherwood Park
CA
Agent
Finnegan Henderson Farabow Garrett & Dunner L
Assignee
Westaim Technologies
CA
IPC
A61F 2/02
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