05679355 is referenced by 25 patents and cites 9 patents.

Non-ionic surfactant vesicles (NSIV) with entrapped antigen act as potent immunological adjuvants and can produce antibody titers of the same order of magnitude as those using Freund's Complete Adjuvant. The invention provides vaccines comprising such vesicles. Preferably non-ionic surfactants are glycerol esters particularly 1-monopalmitoyl glycerol. The vesicles may be administered by injection or via the mucosal route, oral administration being preferred.

Title
Vaccines containing non-ionic surfactant vesicles
Application Number
8/302915
Publication Number
5679355
Application Date
January 5, 1995
Publication Date
October 21, 1997
Inventor
James MacDonald Brewer
Glasgow
GB
James Alexander
Glasgow
GB
Agent
Pennie & Edmonds
Assignee
Proteus Molecular Design
GB
IPC
A61K 47/00
A61K 45/05
A61K 9/10
A61K 45/00
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