05674205 is referenced by 101 patents and cites 26 patents.

Direct injection of sphincteric botulinum toxin is disclosed as an effective, safe and simple method of treatment for disorders of gastrointestinal muscle or smooth muscles elsewhere in the body, with results that appear to be sustained for several months. Muscle disorders which are suitable for such treatment include achalasia, isolated disorders of the lower esophageal sphincter, gastroparesis, hypertrophic pyloric stenosis, sphincter of Oddi dysfunction, short-segment Hirschsprung's, anal fissure, hemorrhoids, proctalgia fugax, irritable bowel syndrome, disorders of the upper esophageal sphincter, vasospastic disorders, and disorders of uterine and bladder spasm. Devices suitable for delivering this therapy are also disclosed.

Title
Device for treating gastrointestinal muscle disorders and other smooth muscle dysfunction
Application Number
112088
Publication Number
5674205
Application Date
April 11, 1995
Publication Date
October 7, 1997
Inventor
Anthony N Kalloo
Glenndale
MD, US
Pankaj J Pasricha
Columbia
MD, US
Agent
Banner & Witcoff
Assignee
The Johns Hopkins University
MD, US
IPC
A61M 5/00
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