05663159 is referenced by 97 patents and cites 16 patents.

There are disclosed novel oral prodrugs of phosphonate nucleotide analogs which are hydrolyzable under physiological conditions to yield compounds which are useful as antiviral agents, especially as agents effective against RNA and DNA viruses. They may also find use as antitumor agents.

Title
Prodrugs of phosphonates
Application Number
583906
Publication Number
5663159
Application Date
October 11, 1994
Publication Date
September 2, 1997
Inventor
Joanne J Bronson
Madison
CT, US
David R Tortolani
Meriden
CT, US
John C Martin
Cheshire
CT, US
Muzammil M Mansuri
Cheshire
CT, US
John E Starrett Jr
Middletown
CT, US
Agent
Max D Hensley
Assignee
Rega Stichting v z w
BE
Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic
CZ
IPC
C07F 9/6584
C07F 9/6512
A61K 31/675
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