05656503 is referenced by 203 patents and cites 196 patents.

An analytical test device useful for example in pregnancy testing, comprises a hollow casing (500) constructed of moisture-impervious solid material, such as plastics materials, containing a dry porous carrier (510) which communicates indirectly with the exterior of the casing via a bibulous sample receiving member (506) which protrudes from the casing such that a liquid test sample can be applied to the receiving member and permeate therefrom to the porous carrier, the carrier containing in a first zone a labelled specific binding reagent is freely mobile within the porous carrier when in the moist state, wherein the mobility is facilitated by a material comprising a sugar, in an amount effective to reduce interaction between the test strip and the labelled reagent, and in a second zone spatially distinct from the first zone unlabelled specific binding reagent for the same analyte which unlabelled reagent is permanently immobilised on the carrier material and is therefore not mobile in the moist state, the two zones being arranged such that liquid sample applied to the porous carrier can permeate via the first zone into the second zone, and the device incorporating means, such as an aperture (508) in the casing, enabling the extent (if any) to which the labelled reagent becomes bound in the second zone to be observed. Preferably the device includes a removable cap for the protruding bibulous member.

Title
Test device for detecting analytes in biological samples
Application Number
294146
Publication Number
5656503
Application Date
September 15, 1994
Publication Date
August 12, 1997
Inventor
Ian Richards
Bedford
GB
Michael Evans Prior
Northamptonshire
GB
Keith May
Bedfordshire
GB
Agent
Cushman Darby & Cushman IP Group of Pillsbury Madison & Sutro
Assignee
Unilever Patent Holdings
NL
IPC
G01N 33/558
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