05637087 is referenced by 112 patents and cites 16 patents.

A prefilled, two-constituent system is provided with a syringe barrel having a dispensing end with an inwardly directed, stationary, piercing cannula. Within the syringe barrel is a first, sealed, collapsible container holding a first constituent at subatmospheric pressure. The first container is slidably disposed within the syringe barrel adjacent the piercing cannula. A second, sealed, collapsible container holding a liquid second constituent is slidably disposed within the syringe barrel spaced from the first container. A carrier is slidably disposed within the syringe barrel between the first and second containers. The carrier has a double-ended, hollow, piercing needle with oppositely extending first and second ends for piercing the first and second containers, respectively. A plunger is slidably mounted within the syringe barrel for applying a force to the second container.

Title
Prefilled, two-constituent syringe
Application Number
8/408767
Publication Number
5637087
Application Date
March 22, 1995
Publication Date
June 10, 1997
Inventor
John M Hofstetter
Vernon Hills
IL, US
John A O Neil
Mundelein
IL, US
Agent
Neal D Marcus
Assignee
Abbott Laboratories
IL, US
IPC
A61M 37/00
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