05628890 is referenced by 958 patents and cites 42 patents.

An electrode strip for use in an electrochemical sensor for measuring a compound in a sample is provided, including an electrode support, a reference or counter electrode disposed on the support, a working electrode spaced from the reference or counter electrode on the support, a covering layer defining an enclosed space over the reference and working electrodes and having an aperture for receiving a sample into the enclosed space, and a plurality of mesh layers interposed in the enclosed space between the covering layer and the support, the covering layer having a sample application aperture spaced from said electrodes and said reference electrode spaced from said working electrode at a position remote from and on the opposite side of said working electrode from said aperture. The working electrode includes an enzyme capable of catalyzing a reaction involving a substrate for the enzyme or a substrate catalytically reactive with an enzyme and a mediator capable of transferring electrons transferred between the enzyme-catalyzed reaction and the working electrode to create a current representative of the activity of the enzyme and representative of the compound.

Title
Electrochemical sensor
Application Number
8/534876
Publication Number
5628890
Application Date
September 27, 1995
Publication Date
May 13, 1997
Inventor
Jared L Watkin
Oxon
GB
Gurdial S Sanghera
Oxford
GB
Steven Scott
Oxon
GB
Graham J Hughes
Oxford
GB
Geoffrey R Chambers
Northwood Middlesex
GB
Nigel F Carter
Oxon
GB
Agent
Fish & Richardson P C
Assignee
MediSense
MA, US
IPC
G01N 27/26
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