05624821 is referenced by 559 patents and cites 1 patents.

An antibody with an altered function, e.g. altered affinity for an effector ligand such as Fc receptor (FcR) on a cell or the C1 component of complement is produced by replacing at least one amino acid residue in the constant portion of the antibody with a different residue.

Title
Antibodies with altered effector functions
Application Number
303668
Publication Number
5624821
Application Date
June 7, 1995
Publication Date
April 29, 1997
Inventor
Dennis R Burton
Sheffield
GB
Alexander R Duncan
Wimbledon
GB
Gregory P Winter
Cambridge
GB
Agent
Spencer & Frank
Assignee
Scotgen Biopharmaceuticals Incorporated
CA, US
IPC
A61K 39/395
C12N 1/20
C12N 15/00
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