05624537 is referenced by 488 patents and cites 3 patents.

A regenerable biosensor probe adapted for positioning in a bioreactor comprises a selectively permeable interface membrane, a porous protein-receiving matrix adjacent to the interface membrane, an indicating electrode, an inlet conduit through which fresh protein conjugate may flow to the protein-receiving matrix, and an outlet conduit through which spent protein conjugate may be removed from the protein-receiving matrix. A selectively permeable interface membrane, which may be used in a biosensor system to separate biochemical, optical or other processes from an analyte matrix comprises a supporting mesh, a perfluorosulfonic acid polymer impregnated substrate and a homogenous film of perfluorosulfonic acid polymer.

A method of preparing this interface membrane comprises fixing a substrate on to a supporting mesh to form a substrate membrane, casting a perfluorosulfonic and polymer on the substrate membrane and curing the product to so formed.

Title
Biosensor and interface membrane
Application Number
8/309338
Publication Number
5624537
Application Date
September 20, 1994
Publication Date
April 29, 1997
Inventor
Michael R Phelps
Kingston
CA
Douglas G Kilburn
Vancouver
CA
Robin F B Turner
Vancouver
CA
Agent
Christensen O Connor Johnson & Kindness PLLC
Assignee
The University of British Columbia University Industry Liaison Office
CA
IPC
G01N 27/26
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