05622871 is referenced by 231 patents and cites 200 patents.

An analytical test device useful for example in pregnancy testing, includes a hollow casing (500) constructed of moisture-impervious solid material, such as plastics materials, containing a dry porous carrier (510) which communicates indirectly with the exterior of the casing via a bibulous sample receiving member (506) which protrudes from the casing such that a liquid test sample can be applied to the receiving member and permeate therefrom to the porous carrier, the carrier containing in a first zone a labelled specific binding reagent is freely mobile within the porous carrier when in the moist state, and in a second zone spatially distinct from the first zone unlabelled specific binding reagent for the same analyte which unlabelled reagent is permanently immobilised on the carrier material and is therefore not mobile in the moist state, the two zones being arranged such that liquid sample applied to the porous carrier can permeate via the first zone into the second zone, and the device incorporating an aperture (508) in the casing, enabling the extent (if any) to which the labelled reagent becomes bound in the second zone to be observed. Preferably the device includes a removable cap for the protruding bibulous member.

Title
Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
Application Number
294146
Publication Number
5622871
Application Date
July 15, 1993
Publication Date
April 22, 1997
Inventor
Ian Richards
Bedford
GB
Michael E Prior
Northamptonshire
GB
Keith May
Bedfordshire
GB
Agent
Cushman Darby & Cushman
Assignee
Unilever Patent Holdings
NL
IPC
G01N 33/558
View Original Source