05620969 is referenced by 11 patents and cites 9 patents.

Novel cephem derivatives represented by the general formula ##STR1## in which the Acyl substituent is a group of the formula ##STR2## wherein Ar is a lipophilic optionally substituted phenyl, naphthyl or pyridyl group; R.sup.1 represents either the residue of a heterocyclic amino acid or a C.sub.2 -C.sub.10 alkyl group substituted by both a carboxyl group and a group of the formula --NR.sup.9 R.sup.10 or ##STR3## in which R.sup.9 and R.sup.10 are each independently hydrogen or C.sub.1 -C.sub.6 alkyl, said C.sub.2 -C.sub.10 alkyl group being optionally interrupted by one or more nitrogen atoms or carbonyl groups, and R.sup.2 and R.sup.3 are each independently hydrogen, alkyl or aminoalkyl are gram-positive antibacterial agents, especially useful in the treatment of diseases caused by methicillin-resistant Staphylococcus aureus (also referred to below as MRSA or methicillin-resistant S. aureus).

Title
Cephalosporin derviatives
Application Number
8/427778
Publication Number
5620969
Application Date
April 25, 1995
Publication Date
April 15, 1997
Inventor
John A Wichtowski
Deep River
CT, US
Yasutsugu Ueda
Clinton
CT, US
Dane M Springer
Madison
CT, US
Bing Y Luh
Killingworth
CT, US
Peter F Misco Jr
Durham
CT, US
John D Matiskella
Wallingford
CT, US
Shelley E Hoeft
Middletown
CT, US
Stanley V D Andrea
Middletown
CT, US
Joanne J Bronson
Madison
CT, US
Agent
David M Morse
Assignee
Bristol Myers Squibb Company
NJ, US
IPC
A61K 31/545
C07D 501/36
View Original Source