05591669 is referenced by 281 patents and cites 2 patents.

Transgenic mice having a phenotype characterized by the substantial depletion of a mature lymphocytic cell type otherwise naturally occurring in the species from which the transgenic mouse is derived. The phenotype is conferred in the transgenic mouse by a transgene contained in at least the precursor stem cell of the lymphocytic cell type which is depleted. The transgene comprised is a DNA sequence encoding a lymphatic polypeptide variant which inhibits maturation of the lymphocytic cell type.

Title
Transgenic mice depleted in a mature lymphocytic cell-type
Application Number
280218
Publication Number
5591669
Application Date
May 30, 1995
Publication Date
January 7, 1997
Inventor
Antonius J M Berns
Spaarndam
NL
Paulus J A Krimpenfort
Amsterdam
NL
Agent
Townsend and Townsend and Crew
Assignee
GenPharm International
CA, US
IPC
C12N 15/00
View Original Source