05585348 is referenced by 84 patents.

This invention relates to a method of preventing hyperalgesia and other undesirable side-effects associated with the administration of growth factor, including nerve growth factor, utilizing an antagonist capable of inactivating excitatory opioid receptor-mediated functions on neurons in the nociceptive pathway. In addition, this invention relates to a composition comprising a growth factor and an antagonist capable of inactivating excitatory opioid receptor-mediated functions on neurons in the nociceptive pathway.

Title
Use of excitatory opioid receptor antagonists to prevent growth factor-induced hyperalgesia
Application Number
97460
Publication Number
5585348
Application Date
August 13, 1993
Publication Date
December 17, 1996
Inventor
Stuart C Apfel
West Hempstead
NY, US
John A Kessler
New Canaan
CT, US
Ke fei Shen
Flushing
NY, US
Stanley M Crain
Leonia
NJ, US
Agent
Amster Rothstein & Ebenstein
Assignee
Albert Einstein College of Medicine of Yeshiva University a Division of Yeshiva University
NY, US
IPC
A61K 38/00
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