05580859 is referenced by 762 patents and cites 10 patents.

Polynucleotide sequences, comprising DNA and RNA molecules can be directly administered, for example by injection, to tissues, such as muscle, and expressed as a protein, polypeptide or polypeptide. The polynucleotides can be contained within liposomes or the polynucleotides can free from association with transfection-facilitating proteins, viral particles, liposomal formulations, charged lipids and calcium phosphate precipitating agents.

Title
Delivery of exogenous DNA sequences in a mammal
Application Number
326305
Publication Number
5580859
Application Date
March 18, 1994
Publication Date
December 3, 1996
Inventor
Dennis A Carson
Del Mar
CA, US
Robert W Malone
Chicago
IL, US
Gary H Rhodes
Leucadia
CA, US
Jon A Wolff
Madison
WI, US
Philip L Felgner
Rancho Santa Fe
CA, US
Agent
Knobbe Martens Olson & Bear
Assignee
Wisconsin Alumni Research Foundation
WI, US
VICAL Incorporated
CA, US
IPC
C12N 15/00
C12P 21/06
A61K 31/70
A01N 43/04
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