05573906 is referenced by 140 patents and cites 4 patents.

A process for the detection of a nucleic acid sequence in a homogeneous assay format using an energy transfer system is disclosed. This process utilizes a 5' labeled primer containing a selfcomplementary sequence in an amplification or extension process together with a subsequent detection step using a 3' labeled probe for the amplified or extended region. The labels will be close together in space after hybridizing the probe close to the short piece of double-stranded DNA resulting from backfolding of the selfcomplementary region of the primer which has been incorporated into the amplified or extended product. A new primer for use in this process is also disclosed.

Title
Detection of nucleic acids using a hairpin forming oligonucleotide primer and an energy transfer detection system
Application Number
8/35010
Publication Number
5573906
Application Date
March 22, 1993
Publication Date
November 12, 1996
Inventor
Francis Muller
Basel
CH
Wilhelm Bannwarth
Upper Saddle River
NJ, US
Agent
Patricia S Rocha Tramaloni
William H Epstein
George M Gould
Assignee
Hoffmann La Roche
NJ, US
IPC
C07H 21/04
C12P 19/34
C12Q 1/68
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