05554148 is referenced by 204 patents and cites 29 patents.

Refillable immunoisolatory neurological therapy devices for local and controlled delivery of a biologically active factor to the brain of a patient. The devices include a cell chamber adapted for infusion with nsecretory cells and having at least one semipermeable or permselective surface across which biologically active factors secreted by the cells can be delivered to the brain. The devices also include means for introducing secretory cells into the cell chamber, and means for renewing the cells or cell medium.

Title
Renewable neural implant device and method
Application Number
121626
Publication Number
5554148
Application Date
May 26, 1995
Publication Date
September 10, 1996
Inventor
Paul J Mulhauser
New York
NY, US
Moses Goddard
Tiverton
RI, US
Paul C DiCesare
Norwalk
CT, US
Patrick Aebischer
Barrington
RI, US
Agent
Ivor R Fish & Neave Elrifi Esq
James F Haley Jr Esq
Assignee
Brown University Research Foundation
RI, US
IPC
A61K 9/22
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