05545516 is referenced by 47 patents and cites 16 patents.

This invention provides methods for inactivating pathogenic contaminants in whole blood, plasma, cellular blood components, or in any combination thereof, by adding a phenthiazin-5-ium dye(s) thereto and irradiating said dye-containing composition for an effective length of time with light of wavelengths from 560 to 800 nm or red light, of an effective intensity, whereby the irradiation in conjunction with the dye(s) inactivate substantially all pathogenic contaminants contained therein. The methods of this invention inactivate pathogenic contaminants, such as viruses, bacteria and parasites, without substantially altering the whole blood, plasma, cellular blood components, or combinations thereof, such that they are suitable for transfusion.

Title
Inactivation of extracellular enveloped viruses in blood and blood components by phenthiazin-5-ium dyes plus light
Application Number
517664
Publication Number
5545516
Application Date
February 18, 1994
Publication Date
August 13, 1996
Inventor
Stephen J Wagner
Columbia
MD, US
Agent
Sterne Kessler Goldstein & Fox
Assignee
The American National Red Cross
DC, US
IPC
A61K 35/18
A61K 35/16
A61K 35/14
A01N 1/02
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