05540730 is referenced by 689 patents and cites 10 patents.

Apparatus for treating patients with motility disorders applies a modulating signal to the patient's vagus nerve to stimulate or inhibit neural impulses and produce excitatory or inhibitory neurotransmitter release by the vagus nerve according to the specific nature of the motility disorder. The apparatus includes a neurostimulator which can be activated to generate an electrical output signal. The neurostimulator is responsive to the sensing of a selected event having occurred which is indicative of the need for treatment of the motility disorder, and includes an activation element which responds to sensing of that event to activate the neurostimulator, and a lead with an electrode array to apply the electrical output signal as the modulating signal to the patient's vagus nerve. Certain parameters of the output signal are programmable, and the neurostimulator can be calibrated according to the specific patient and the specific motility disorder being treated. One form of sensor detects the impedance of a selected part of the gastrointestinal system to detect the presence of excessive contractions in that part as an indication of hypermotility whether or not food has been consumed by the patient within a preset interval of time, and inadequate contractions in that part as an indication of hypomotility if food was consumed by the patient within a preset interval of time.

Title
Treatment of motility disorders by nerve stimulation
Application Number
8/469174
Publication Number
5540730
Application Date
June 6, 1995
Publication Date
July 30, 1996
Inventor
Andre Marquette
Stamford
CT, US
Ross G Baker Jr
Houston
TX, US
Reese S Terry Jr
Houston
TX, US
Agent
Wigman Cohen Leitner & Myers P C
Assignee
Cyberonics
TX, US
IPC
A61N 1/40
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