05540727 is referenced by 324 patents and cites 12 patents.

A cardiac stimulating system incorporating a microprocessor-based controller is designed to automatically optimize both the pacing mode and one or more pacing cycle parameters in a way that results in optimization of a cardiac performance parameter, such as cardiac output. For each of a plurality of modes in which a DDD cardiac pacer can operate, a pacing parameter such as the AV interval of the pacer is incrementally adjusted and following that, an observation is made as to the effect of the adjustment on cardiac output. After the process has been repeated for all possible pacing modes, a determination is made to find the pacing mode and the AV interval or other pacing parameter that results in the maximum cardiac output or other optimal cardiac performance parameter. It is these pacing parameters that are then programmed into the microcontroller for causing the pacemaker to function in the desired mode and at the desired parameter values.

Title
Method and apparatus to automatically optimize the pacing mode and pacing cycle parameters of a dual chamber pacemaker
Application Number
8/339813
Publication Number
5540727
Application Date
November 15, 1994
Publication Date
July 30, 1996
Inventor
Rodney W Salo
Fridley
MN, US
Julio C Spinelli
Shoreview
MN, US
Bruce A Tockman
Minneapolis
MN, US
Agent
Haugen and Nikolai P A
Assignee
Cardiac Pacemakers
MN, US
IPC
A61N 1/365
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