05536237 is referenced by 40 patents and cites 3 patents.

A method and system for calibrating and controlling the withdrawal of a fluid, such as blood, from a fluid source, such as a blood vessel, includes a fluid pump, a pressure sensor, a flow rate sensor, and a microprocessor based flow control subsystem. The flow control subsystem optimizes the flow rate by sensing zero flow rate pressure within the subject, making a plurality of periodic flow path pressure measurements and extrapolating a calibration flow rate curve. A control curve is generated by utilizing the zero-flow rate pressure point, the slope of the calibration curve, and an empirically predetermined pressure. The blood pump is then operated at a maximum speed that is limited by the flow control curve to maximize flow without occlusion or collapse of the blood vessel during blood withdrawal. The method and system of the invention is particularly applicable to automated apheresis systems.

Title
Blood extraction flow control calibration system and method
Application Number
7/891527
Publication Number
5536237
Application Date
June 1, 1992
Publication Date
July 16, 1996
Inventor
Robin Huff
Costa Mesa
CA, US
Paul R Prince
San Juan Capistrano
CA, US
Agent
Bruce M Canter
Assignee
Baxter International
IL, US
IPC
A61M 1/03
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