05529066 is referenced by 45 patents and cites 13 patents.

A capsule for encapsulating implantable cells for improving the detectability of electrical signals generated by the cells is provided. The capsule includes a low-conductivity (high electrical resistance) membrane and a semi-permeable (low electrical resistance) membrane. The low-conductivity membrane seals around the circumference of the cell mass between the electrical poles of the capsule, and further extends for increasing the electrical resistance between the poles. The semi-permeable membrane enables nutrients and waste materials to flow to and from the cell mass. The semi-permeable membrane encloses at least one of the poles of the cell mass, and cooperates with the low-conductivity membrane to completely enclose the cell mass. The low-conductivity membrane may enclose one of the poles, if desired. Electrodes are used to detect the electrical signals from the cell mass. Various methods of making the capsule are disclosed.

Title
Implantable capsule for enhancing cell electric signals
Application Number
8/266204
Publication Number
5529066
Application Date
June 27, 1994
Publication Date
June 25, 1996
Inventor
Yoram Palti
Haifa
IL
Agent
David M Klein
Bryan Cave
Assignee
CB Carmel Biotechnology
IL
IPC
A61B 5/05
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