05525338 is referenced by 73 patents and cites 5 patents.

Methods are provided for detecting and/or treating lesions in a patient. The methods use a targeting composition comprised of a biotin and targeting protein conjugate or an avidin and targeting protein conjugate; optionally, a clearing composition comprised of avidin, when the targeting composition is a biotin conjugate, or biotin, when the targeting composition is a avidin conjugate; a detection or therapeutic composition comprised of a conjugate of avidin or biotin with a targeting protein and detection or therapeutic agent; and, optionally, another detection or therapeutic composition comprised of avidin or biotin conjugated to a detection or therapeutic agent. Compositions and kits useful in the methods are also provided.

Title
Detection and therapy of lesions with biotin/avidin conjugates
Application Number
7/933982
Publication Number
5525338
Application Date
August 21, 1992
Publication Date
June 11, 1996
Inventor
David M Goldenberg
Short Hills
NJ, US
Agent
Foley & Lardner
Assignee
Immunomedics
NJ, US
IPC
A61K 39/44
A61K 39/385
A61K 38/27
A61K 38/18
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