05519134 is referenced by 434 patents and cites 3 patents.

Novel pyrrolidine monomers bearing various functional groups are used to prepare oligomeric structures. The pyrrolidine monomers can be joined via standard phosphate linkages including phosphodiester and phosphorothioate linkages. Useful functional groups include nucleobases as well as polar groups, hydrophobic groups, ionic groups, aromatic groups and/or groups that participate in hydrogen-bonding.

Title
Pyrrolidine-containing monomers and oligomers
Application Number
8/180134
Publication Number
5519134
Application Date
January 11, 1994
Publication Date
May 21, 1996
Inventor
Normand Hebert
San Marcos
CA, US
Oscar L Acevedo
San Diego
CA, US
Agent
Woodcock Washburn Kurtz Mackiewicz & Norris
Assignee
Isis Pharmaceuticals
CA, US
IPC
C07D 239/26
C07D 233/60
C07D
C07D
C07D 207/10
C07D 207/06
C07D 207/08
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