05512435 is referenced by 14 patents and cites 4 patents.

Methods and composition are provided for identifying antiproliferative polypeptides which inhibit clonal expansion and/or induce apoptosis in cells of a predetermined cell population (e.g., a neoplastic cell sample) expressing a cell surface receptor which is a member of the immunoglobulin superfamily. A predetermined cell population expressing surface immunoglobulin superfamily molecules is isolated from a patient as a cellular sample, such as a lymph node biospy or blood sample containing neoplastic lymphocytic cells. Antiproliferative peptides which are identified by the methods of the invention can be used as therapeutic agents for treating lymphoproliferative disorders by anti-idiotype therapy.

Title
Receptor-binding antiproliferative peptides
Application Number
8/14426
Publication Number
5512435
Application Date
February 5, 1993
Publication Date
April 30, 1996
Inventor
William J Dower
761 Partridge Ave., Menlo Park, 94025
CA, US
Ramesh R Bhatt
777 W. Middlefield #18, Mountain View, 94025
CA, US
Ronald Levy
966 Mears Ct., Stanford, 94043
CA, US
Markus F Renschler
731 Alameda De Las Pulgas, Redwood City, 94063
CA, US
Agent
Tracy J Dunn
IPC
C12Q 1/68
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