05491170 is referenced by 7 patents and cites 7 patents.

.beta.-Carboxy sulfonyl compounds of the formula ##STR1## wherein R.sub.1 is aryl, R.sub.3 is hydrogen or alkyl, R.sub.3 and R.sub.4 are hydrogen or alkyl, Y is --O--, --S--, or --NR.sub.2 --, and R.sub.5 is alkyl or aryl are potent inhibitors of the enzyme acyl CoA:cholesterol acyltransferase (ACAT) and are thus useful for treating hypercholesterolemia and atherosclerosis.

Title
.beta.-carboxy sulfonamide ACAT inhibitors
Application Number
8/359115
Publication Number
5491170
Application Date
December 19, 1994
Publication Date
February 13, 1996
Inventor
Drago R Sliskovic
Ypsilanti
MI, US
Joseph A Picard
Canton
MI, US
Helen T Lee
Ann Arbor
MI, US
Agent
Charles W Ashbrook
Assignee
Warner Lambert Company
NJ, US
IPC
C07C 311/25
A61K 31/215
A61K 31/19
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