05491084 is referenced by 276 patents.

This invention provides a cell comprising a DNA molecule having a regulatory element from a gene, other than a gene encoding a green-fluorescent protein operatively linked to a DNA sequence encoding the green-fluorescent protein. This invention also provides a method for selecting cells expressing a protein of interest which comprises: a. introducing into the cells a DNAI molecule having DNA sequence encoding the protein of interest and DNAII molecule having DNA sequence encoding a green-fluorescent protein; b. culturing the introduced cells in conditions permitting expression of the green-fluorescent protein and the protein of interest; and c. selecting the cultured cells which express green-fluorescent protein, thereby selecting cells expressing the protein of interest. Finally, this invention provides various uses of a green-fluorescent protein.

Title
Uses of green-fluorescent protein
Application Number
8/119678
Publication Number
5491084
Application Date
September 10, 1993
Publication Date
February 13, 1996
Inventor
Douglas Prasher
East Falmouth
MA, US
Martin Chalfie
New York
NY, US
Agent
John P White
Assignee
Woods Hole Oceanographic Institution
MA, US
The Trustees of Columbia University in the City of New York
NY, US
IPC
C07H 19/00
C12P 21/06
C12N 5/00
C12N 9/02
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