05490840 is referenced by 59 patents and cites 14 patents.

Thermal drug treatment of tumor tissue is obtained by attaching a thermally active drug to carrier molecules which have an affinity to tumor tissue. Localized heating is performed on the tumor tissue, thereby activating the drug in the tumor tissue. The end result may be concentrated delivery of a drug to a chosen tissue, or, in the case where the drug creates a toxin when heated, selective tissue destruction of a selected locations heated. The localized heat may be applied by focused ultrasound heating.

Title
Targeted thermal release of drug-polymer conjugates
Application Number
8/312362
Publication Number
5490840
Application Date
September 26, 1994
Publication Date
February 13, 1996
Inventor
Harvey E Cline
Niskayuna
NY, US
Thomas R Anthony
Niskayuna
NY, US
Kirby G Vosburgh
Niskayuna
NY, US
Lorinda R Opsahl
Clifton Park
NY, US
Egidijus E Uzgiris
Niskayuna
NY, US
Agent
Marvin Snyder
Lawrence P Zale
Assignee
General Electric Company
NY, US
IPC
A61B 17/20
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