05479920 is referenced by 303 patents and cites 20 patents.

An apparatus for delivering medicinal aerosol on-demand during patient inhalation wherein delivery of aerosol from a nebulizer (22) is optimized by synchronizing delivery to the inspiration of a patient (58)is disclosed. A control unit (32) monitors airway pressure and controls the flow of gas so that aerosol delivery is triggered by patient inhalation, in which event delivery continues for a predetermined time period which is adjustable by the user. The apparatus can be used with a mouthpiece (56), a face mask (66) without an integral exhalation valve, or a face mask (68) with an integral exhalation valve. The apparatus significantly increases the efficiency of delivery of medicinal aerosol by sensing a patient's inhalation and exhalation cycles and delivering aerosol only after a certain inhalation pressure is sensed following a certain previous exhalation pressure. These pressures, which are compared against predetermined thresholds, correspond to the actual patient breathing condition. By monitoring the patient's inhalation and exhalation in this manner, aerosol delivery is synchronized with the patient's breathing pattern. In this way, the apparatus prevents aerosol contamination of the environment without requiring an exhalation filter since aerosol is delivered to the patient only during inhalation. Exhalation is not obstructed since aerosol is not delivered during exhalation. Further, when it is desirable to use an exhalation filter to reduce the amount of exhalation gas discharged into the environment, the apparatus reduces occlusion occurring in the exhalation filter.

Title
Breath actuated medicinal aerosol delivery apparatus
Application Number
8/205598
Publication Number
5479920
Application Date
March 1, 1994
Publication Date
January 2, 1996
Inventor
Gordon A Wong
Sacramento
CA, US
James I C Lee
Sacramento
CA, US
Samuel D Piper
Sacramento
CA, US
Agent
John P O Banion
Assignee
Vortran Medical Technology
CA, US
IPC
A61M 16/00
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