05475096 is referenced by 332 patents and cites 2 patents.

A new class of nucleic acid compounds, referred to as nucleic acid ligands, have been shown to exist that have a specific binding affinity for three dimensional molecular targets. In a preferred embodiment the nucleic acid ligands are identified by the method of the invention referred to as the Systematic Evolution of Ligands by EXponential enrichment (SELEX), wherein a candidate mixture of nucleic acids are iteratively enriched in high affinity nucleic acids and amplified for further partitioning.

Title
Nucleic acid ligands
Application Number
536428
Publication Number
5475096
Application Date
June 10, 1991
Publication Date
December 12, 1995
Inventor
Craig Tuerk
Boulder
CO, US
Larry Gold
Boulder
CO, US
Agent
Swanson & Bratschun
Assignee
University Research Corporation
CO, US
IPC
C07H 21/02
C07H 21/04
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