05464650 is referenced by 867 patents and cites 28 patents.

A method for making an intravascular stent by applying to the body of a stent a solution which includes a solvent, a polymer dissolved in the solvent and a therapeutic substance dispersed in the solvent and then evaporating the solvent. The inclusion of a polymer in intimate contact with a drug on the stent allows the drug to be retained on the stent during expansion of the stent and also controls the administration of drug following implantation. The adhesion of the coating and the rate at which the drug is delivered can be controlled by the selection of an appropriate bioabsorbable or biostable polymer and the ratio of drug to polymer in the solution. By this method, drugs such as dexamethasone can be applied to a stent, retained on a stent during expansion of the stent and elute at a controlled rate.

Title
Intravascular stent and method
Application Number
8/52878
Publication Number
5464650
Application Date
April 26, 1993
Publication Date
November 7, 1995
Inventor
Rodney G Wolff
Minnetonka Beach
MN, US
Michael Dror
Edina
MN, US
Ronald J Tuch
Plymouth
MN, US
Eric P Berg
Plymouth
MN, US
Agent
Harold R Patton
Daniel W Latham
Assignee
Medtronic
MN, US
IPC
B05D 1/38
B05D 1/18
B05D 1/02
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