05456693 is referenced by 277 patents and cites 6 patents.

A bioresorbable and hemostatic plug for embolization made from a collagen piece is compressed so as to be longitudinally insertable into a tubular biological vessel such as a blood vessel to be occluded. The collagen piece is capable of expanding radially inside the vessel by absorbing fluid such as the blood and thereby providing mechanical fixation in and occlusion of the vessel. Two such collagen pieces may be used with a spacer of a different material in between. Different kinds of therapeutic agents can be bonded to or physically absorbed by the collagen pieces so as to be delivered to the site of occlusion.

Title
Embolization plugs for blood vessels
Application Number
948235
Publication Number
5456693
Application Date
August 25, 1994
Publication Date
October 10, 1995
Inventor
Ronald Yamamoto
San Francisco
CA, US
Jennifer Raeder Devens
Oakland
CA, US
Aileen L Murphy
Menlo Park
CA, US
Gregory S Dapper
Newark
CA, US
Stanley R Conston
San Carlos
CA, US
Agent
Fish & Richardson
Assignee
Vitaphore Corporation
NJ, US
IPC
A61L 15/00
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