05454886 is referenced by 122 patents and cites 25 patents.

Anti-microbial coatings and powders and method of forming same on medical devices are provided. The coatings are formed by depositing an anti-microbial biocompatible metal by vapour deposition techniques to produce atomic disorder in the coating such that a sustained release of metal ions sufficient to produce an anti-microbial effect is achieved. Preferred deposition conditions to achieve atomic disorder include a lower than normal substrate temperature, and one or more of a higher than normal working gas pressure and a lower than normal angle of incidence of coating flux. Anti-microbial powders formed by mechanical working to produce atomic disorder are also provided. The anti-microbial effect of the coatings or powders may be further activated or enhanced by irradiating with a low linear energy transfer form of radiation such as gamma radiation.

Title
Process of activating anti-microbial materials
Application Number
8/154490
Publication Number
5454886
Application Date
November 18, 1993
Publication Date
October 3, 1995
Inventor
Larry R Morris
Yarker
CA
Catherine L McIntosh
Sherwood Park
CA
Robert E Burrell
Sherwood Park
CA
Agent
Finnegan Henderson Farabow Garrett & Dunner
Assignee
Westaim Technologies
CA
IPC
A61M 5/32
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