05437291 is referenced by 228 patents and cites 13 patents.

Direct injection of sphincteric botulinum toxin is disclosed as an effective, safe and simple method of treatment for disorders of gastrointestinal muscle or smooth muscles elsewhere in the body, with results that appear to be sustained for several months. Muscle disorders which are suitable for such treatment include achalasia, isolated disorders of the lower esophageal sphincter, gastroparesis, hypertrophic pyloric stenosis, sphincter of Oddi dysfunction, short-segment Hirschsprung's, anal fissure, hemorrhoids, proctalgia fugax, irritable bowel syndrome, disorders of the upper esophageal sphincter, vasospastic disorders, and disorders of uterine and bladder spasm. Devices suitable for delivering this therapy are also disclosed.

Title
Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction
Application Number
8/112088
Publication Number
5437291
Application Date
August 26, 1993
Publication Date
August 1, 1995
Inventor
Anthony N Kalloo
10708 Forestgate Pl., Glenndale, 20769
MD, US
Pankai J Pasricha
5007 Southern Star Ter., Columbia, 21044
MD, US
IPC
A61B 19/00
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