Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction United States Patent 05437291

05437291 is referenced by 233 patents and cites 13 patents.

Direct injection of sphincteric botulinum toxin is disclosed as an effective, safe and simple method of treatment for disorders of gastrointestinal muscle or smooth muscles elsewhere in the body, with results that appear to be sustained for several months. Muscle disorders which are suitable for such treatment include achalasia, isolated disorders of the lower esophageal sphincter, gastroparesis, hypertrophic pyloric stenosis, sphincter of Oddi dysfunction, short-segment Hirschsprung's, anal fissure, hemorrhoids, proctalgia fugax, irritable bowel syndrome, disorders of the upper esophageal sphincter, vasospastic disorders, and disorders of uterine and bladder spasm. Devices suitable for delivering this therapy are also disclosed.

Title
Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction
Application Number
8/112088
Publication Number
5437291
Application Date
August 26, 1993
Publication Date
August 1, 1995
Inventor
Anthony N Kalloo
10708 Forestgate Pl., Glenndale, 20769
MD, US
Pankai J Pasricha
5007 Southern Star Ter., Columbia, 21044
MD, US
IPC
A61B 19/00
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Citations: 233 (view full list)

  1. Eric First, M.D.
    Eric R First: toxin treatment for kinesia. Allergan, Claude L Nassif, Stephen Donovan, Martin A Voet, September 18, 2007: US07270287 (15 worldwide citation)
  2. Eric First, M.D.
    Eric R First: Botulinum toxin therapy for skin disorders. Allergan, Hal Gibson, Debra Condino, November 1, 2011: US08048423 (9 worldwide citation)
  3. Eric First, M.D.
    Eric R First: Methods for treating eye disorders. Allergan, Claude L Nassif, Stephen Donovan, Martin Voet, December 16, 2008: US07465458 (7 worldwide citation)
  4. Eric First, M.D.
    Eric R First: Methods and compositions for treating eye disorders. Allergan, Claude L Hassif, Stephen Donovan, Martin A Voet, May 22, 2007: US07220422 (7 worldwide citation)
  5. Eric First, M.D.
    Eric R First: Stretch mark treatment. Allergan, Claude L Nassif, Stephen Donovan, Martin Voet, September 30, 2008: US07429386 (7 worldwide citation)
  6. Eric First, M.D.
    Eric R First: Cosmetic neurotoxin compositions and methods. Allergan, Brigitte C Phan, Ted Chan, Debra Condino, February 11, 2014: US08647639 (5 worldwide citation)
  7. Eric First, M.D.
    Eric R First: Buttock deformity treatment. Allergan, Claude L Nassif, Stephen Donovan, Martin Voet, October 21, 2008: US07438921 (3 worldwide citation)
  8. Eric First, M.D.
    Eric R First: Methods for treating a buttock deformity. Allergan, Stephen Donovan, February 20, 2007: US07179474 (3 worldwide citation)
  9. Eric First, M.D.
    Eric R First, Ryan A Irvine: Methods for enhancing therapeutic effects of a neurotoxin. Allergan, Claude L Nassif, Kenton Abel, Debra Condino, November 2, 2010: US07824694 (3 worldwide citation)
  10. Eric First, M.D.
    Eric R First: Cosmetic neurotoxin compositions and methods. Allergan, Brigitte C Phan, Ted A Chan, Debra D Condino, June 16, 2015: US09056059

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