05432272 is referenced by 429 patents and cites 2 patents.

The disclosure describes a method for incorporating into double stranded DNA and RNA base pairs composed of pairing units that fit the Watson-Crick geometry in that they involve a monocyclic six membered ring pairing with a fused bicyclic heterocyclic ring system composed of a five member ring fused with a six membered ring, with the orientation of the heterocycles with respect to each other and with respect to the backbone chain analogous to that found in DNA and RNA, but with a pattern of hydrogen bonds holding the base pair together different from that found in the AT and GC base pairs (a "non-standard base pair").

Title
Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases
Application Number
7/594290
Publication Number
5432272
Application Date
October 9, 1990
Publication Date
July 11, 1995
Inventor
Steven A Benner
Hadlaubstrasse 151, CH-8006 Zurich
CH
IPC
C12P 19/34
C07H 23/00
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