05424332 is referenced by 45 patents.

A pharmaceutical composition in dosage form for treating psoriasis and psoriatic arthritis includes, essentailly, as active substance (s), a fumaric acid monoalkylester salt having the formula ##STR1## wherein R is a methyl, propyl or isopropyl group, and M.sup.++ is calcium, alone or in combination with at least one of the fumaric acid alkyl ester salts as defined above, M.sup.++ is selected from the group consisting of magnesium, zinc and iron. The combination includes, by weight, 10-250 parts, 0-50 parts magnesium, and 0-50 parts zinc or iron salt of fumaric acid monoalkylester, in an amount of fumaric acid not exceeding 300 mg. per dosage form, in combination with ordinary pharmaceutically compatible solid adjuvants and vehicles.

Title
Pharmaceutical composition and process for the production thereof
Application Number
109780
Publication Number
5424332
Application Date
August 31, 1993
Publication Date
June 13, 1995
Inventor
Rajendra K Joshi
Alstetterstrasse 224, 8048 Zurich
CH
Peter P Speiser
Freudenbergstrasse 101/D2, 8044 Zurich
CH
Agent
Cohen Pontani Lieberman Pavane
IPC
A61K 31/315
A01N 55/02
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