05411952 is referenced by 75 patents and cites 22 patents.

Cyclosporine compositions for topical ophthalmic use for treatment of immune disorders, to enhance or restore tear production, and to enhance or effect normal healing of the surface of the eye, containing cyclosporine dissolved in corn oil. The composition may further include antioxidants, lubricants, antibiotics, antifungals, antivirals, pilocarpine, vasoconstrictors, surfactants, wetting agents, anti-inflammatory agents (i.e. corticosteroids), preservatives, mucolytic agents (i.e. bromhexine, acetylcysteine), as well as other compounds.

The preferred composition is 2% cyclosporine, 1 mole % alpha tocopherol and 0.005% methyl paraben in corn oil.

Title
Ocular cyclosporine composition
Application Number
117218
Publication Number
5411952
Application Date
February 6, 1990
Publication Date
May 2, 1995
Inventor
Renee Kaswan
Athens
GA, US
Agent
Kilpatrick & Cody
Assignee
University of Georgia Research Foundation
GA, US
IPC
A61K 37/02
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