05383467 is referenced by 275 patents and cites 38 patents.

A catheter comprising a unitary guidewire and single mode optical fiber is used to illuminate human body channels, such as a tissue mass within a blood vessel, for purposes of diagnosis. A low coherent light source illuminates the tissue and provides a reference beam. Illumination that is reflected from the tissue is combined with the reference beam in an interferometer process. The path length of the reference beam is changed in a known manner in order to provide a known reference to the distance inside of the tissue from which reflected radiation is being received, thus providing information as to both the nature and the geometry of the tissue. A high signal to noise ratio is provided.

Title
Guidewire catheter and apparatus for diagnostic imaging
Application Number
7/977985
Publication Number
5383467
Application Date
November 18, 1992
Publication Date
January 24, 1995
Inventor
James S Sharrow
Bloomington
MN, US
Jeffrey A McBroom
Champlin
MN, US
Richard C Gunderson
Maple Grove
MN, US
Peter T Fettig
St. Louis Park
MN, US
Victor I Chornenky
Edina
MN, US
Michael L Auer
Chanhassen
MN, US
Agent
Schwegman Lundberg & Woessner
Assignee
SpectraScience
MN, US
IPC
A61B 6/00
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