05380299 is referenced by 436 patents and cites 18 patents.

An intravascular medical device having a structure shaped and sized for introduction into the vascular system of a patient including a base material and a coating of a thrombolytic agent on the base material. The thrombolytic agent advantageously dissolves or breaks up the formation of thrombus on the surface of the structure when placed in the vascular system of a patient. The intravascular medical device also includes a antithrombogenic agent for inhibiting the formation of thrombus on the surface of the medical device. The method of treating a medical device with a thrombolytic agent includes providing a base material for the medical device along with a thrombolytic agent. The base material is dipped into the thrombolytic agent and then removed to allow the thrombolytic agent to dry on the surface thereof. The dipping and drying steps are repeated to increase the concentration or quantity of the thrombolytic agent on the device.

Title
Thrombolytic treated intravascular medical device
Application Number
8/114261
Publication Number
5380299
Application Date
August 30, 1993
Publication Date
January 10, 1995
Inventor
William D Voorhees III
West Lafayette
IN, US
Anthony O Ragheb
West Lafayette
IN, US
Neal E Fearnot
West Lafayette
IN, US
Agent
Richard J Godlewski
Assignee
MED Institute
IN, US
IPC
A61M 5/32
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