05372133 is referenced by 598 patents and cites 12 patents.

Implantable biomedical sensor device for measuring in vivo the presence and/or concentration of physiological substances, such as the concentration of glucose, in a human or animal body. A miniaturized electronic responder (1) arranged in a closed housing (2) of biocompatible material in an electromagnetic interrogation field is capable of contactlessly exchanging binary coded information with a transmitter/receiver, and includes electrical connections (4, 5, 6) passed through the wall of the housing, at least a work electrode (10), a counter-electrode (8) and preferably also a reference electrode (9) outside the housing. The work electrode includes a membrane (13) with hollow fibers extending transversely to the surface of the membrane and having internal walls coated with a conductive polymer (15) and in which a redox enzyme (16) is disposed. One end of the hollow fibers is in electrical contact with a processing device (20) which converts the signals supplied by the work electrode in operation to binary signals.

Title
Implantable biomedical sensor device, suitable in particular for measuring the concentration of glucose
Application Number
8/12860
Publication Number
5372133
Application Date
February 3, 1993
Publication Date
December 13, 1994
Inventor
Johannes H L Hogen Esch
Aalten
NL
Agent
Jacobson Price Holman & Stern
Assignee
N V Nederlandsche Apparatenfabriek Nedap
NL
IPC
A61B 5/00
A61B 5/07
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