Combined perfusion and oxygenation organ preservation apparatus United States Patent 05356771

05356771 is referenced by 67 patents and cites 15 patents.

A method and apparatus is provided for long-term extracorporeal preservation of living tissue. A tissue preservation device including a gas permeable membrane and perfusate allows oxygenation of the living tissue. The gas permeable membrane allows gas from a cyclically pumped source to permeate and expand the membrane, simultaneously oxygenating the perfusate and pumping the oxygen-enriched perfusate through the tissue. Simply constructed of a few basic components, the tissue preservation device is capable of operating in many physical orientations, and requires no electrical power for operation. Also provided is an apparatus for cooling and transporting the tissue preservation device.

Title
Combined perfusion and oxygenation organ preservation apparatus
Application Number
8/29881
Publication Number
5356771
Application Date
March 11, 1993
Publication Date
October 18, 1994
Inventor
Bobby J O Dell
San Antonio
TX, US
Agent
Arnold White & Durkee
Assignee
Board of Regents The University of Texas System
TX, US
IPC
A01N 1/02
View Original Source

Citations: 67 (view full list)

  1. William W Gardetto, John K Heacox, James L Matthews: Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate. Trans D A T A Service, James L Mayor Day Caldwell and Keeton L Jackson, October 12, 1999: US05965433 (93 worldwide citation)
  2. Lauren Brasile, Jolene Clarke: Method and solution for organ preservation comprising retinal-derived growth factor, cyclodextrin, mucopolysaccharide and fluorocarbon. Alliance Pharmaceutical, Knobbe Martens Olson & Bear, December 30, 1997: US05702881 (60 worldwide citation)
  3. Jaak M O Minten: Heart preservation and transportation apparatus and method employing low rate cardiac pacing for improved removal of catabolites from the myocardium. Medtronic, Michael J Jaro, Harold Patton, February 10, 1998: US05716378 (56 worldwide citation)
  4. Donald R Owen, David C Kravitz, John Brassil, Kelvin G M Brockbank, Andrew Burroughs, Dickon Isaacs, Dennis J Steibel, Richard Fraser, Stanley Harris, Douglas Schein: Apparatus and method for maintaining and/or restoring viability of organs. Lifeline Scientific, Oliff & Berridge, November 2, 2010: US07824848 (33 worldwide citation)
  5. Waleed H Hassanein, Richard L Bringham, Ronald L Taylor Jr: Heart preservation chamber. TransMedic, Hamilton Brook Smith & Reynolds P C, August 11, 2009: US07572622 (27 worldwide citation)
  6. Robert Fishman, Robert Havener, Ihab Abdel Fattah, Anas Abdelazim, Scott Newell, Tom Bishop, Tamer Khayal, Stanley Kyi, Ron Taylor, Doug Harriott, Matthew De Remer, Paul Murray, John Sullivan, Mark Anderson, Richard Bringham, Michael Van Driel, Waleed Hassanein: Systems and methods for ex vivo lung care. TransMedics, Wilmer Cutler Pickering Hale and Dorr, April 16, 2013: US08420380 (22 worldwide citation)
  7. Waleed Hassanein, Richard Bringham, Giovanni Cecere, Ahmed Elbetanony, Robert Fishman, Larry Goff, Tamer Khayal, Stanley Kyi, Scott Newell, Burt Ochs, Dennis Sousa, Ronald Taylor, Jonathan Rourke, Hossam Algamil, David Carpenter, Robert Havner, Dmitri Menn: Systems and methods for ex-vivo organ care. TransMedics, Wilmer Cutler Pickering Hale and Dorr, June 18, 2013: US08465970 (22 worldwide citation)
  8. David Walter Wright, Douglas Schein, John Brassil: Method and apparatus for controlling air pressure in an organ or tissue container. Organ Recovery Systems, Oliff & Berridge, March 16, 2010: US07678563 (20 worldwide citation)
  9. John Brassil, Douglas Schein, Christopher Curtis: Method of determining that an organ is not suitable for transplantation and using it for testing substances. Lifeline Scientific, Oliff & Berridge, July 6, 2010: US07749693 (16 worldwide citation)
  10. Michael John Taylor, John Brassil: Method for perfusing an organ and for isolating cells from the organ. Organ Recovery Systems, Oliff & Berridge, March 17, 2009: US07504201 (16 worldwide citation)

References: 15 (view full list)

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