Described herein is an endoscopic instrument such as a dissector, scissor or grasper in which there is provided a shaft which defines a longitudinal axis of the instrument. This shaft is able to rotate about the handle portion of the instrument. This mechanism also provides for articulation of the end effectors with respect to the longitudinal axis of the shaft. This articulation is accomplished by causing angulation of the end effector with respect to the shaft. Because driving the cable is accomplished around any such angle, the end effectors continue to be able to operate. There is disclosed herein a locking mechanism which allows the rotational aspect of the device to operate to rotate the entire articulating mechanism.