05322520 is referenced by 203 patents and cites 20 patents.

An iontophoretic structure for medical devices is provided that uses controlled electrical current derived from two dissimilar galvanic materials to drive oligodynamic metal ions into solution to kill bacteria on and near the device to which the structure is affixed. In one embodiment, a first galvanic material separated from a second galvanic material by a resistive material produces an anti-bacterial current flow when placed in contact with an electrolytic fluid. In another embodiment, a cylindrical elastomeric catheter incorporates a first and a second galvanic material separated by a resistive material which controls a current flow between the galvanic materials when the catheter is immersed in an electrolytic fluid. The galvanic materials can be dissimilar metal powders embedded in a conductive polymer substrate that forms an iontophoretic composite material, or dissimilar metals arranged in layers separated by a resistive layer. In yet another embodiment, the iontophoretic composite material is configured as an infection control sleeve that covers a portion of an ordinary catheter or cannula. Methods of protecting implantable medical devices and body structures with the iontophoretic structures are also provided.

Title
Iontophoretic structure for medical devices
Application Number
7/975597
Publication Number
5322520
Application Date
November 12, 1992
Publication Date
June 21, 1994
Inventor
Fredric L Milder
Brookline
MA, US
Agent
Weingarten Schurgin Gagnebin & Hayes
Assignee
Implemed
MA, US
IPC
A61M 5/32
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