05320808 is referenced by 275 patents and cites 48 patents.

A semi-automated biological sample analyzer and subsystems are provided to simultaneously perform a plurality of enzyme immuno assays for human IgE class antibodies specific to a panel of preselected allergens in each of a plurality of biological samples. A carousel is provided to position and hold a plurality of reaction cartridges. Each reaction cartridge includes a plurality of isolated test sites formed in a two dimensional array in a solid phase binding layer contained within a reaction well which is adapted to contain a biological sample to be assayed. The carousel and cartridges contain structures which cooperate to precisely position the cartridges in each of three separate dimensions so that each cartridge is positioned uniformly. An optical reader operating on a principle of diffuse reflectance is provided to read the results of the assays from each test site of each cartridge. Also provided is a subsystem which provides predetermined lot-specific assay calibration data which is useful for normalizing the results of various assays with respect to predetermined common standard values.

Title
Reaction cartridge and carousel for biological sample analyzer
Application Number
7/227590
Publication Number
5320808
Application Date
August 2, 1988
Publication Date
June 14, 1994
Inventor
Carl W Merkh
Lindenhurst
IL, US
Tung Ming Huang
Elk Grove Village
IL, US
Caryn G Putterman
Northbrook
IL, US
Enrique Hicaro Jr
Chicago
IL, US
James T Holen
Mundelein
IL, US
Agent
Lawrence S Pope
Assignee
Abbott Laboratories
IL, US
IPC
G01N 21/13
G01N 21/01
View Original Source