05312453 is referenced by 121 patents and cites 15 patents.

A rate-responsive cardiac pacemaker in which deceleration of the pacing rate is modulated according to recent patient activity or "work". Based on signals provided from an activity sensor in the pacemaker, the pacemaker maintains and periodically recomputes a work value corresponding to the amount of patient activity detected over time. In response to a decrease in or cessation of detected patient activity, the pacemaker reduces the pacing rate, first at a more rapid deceleration rate, then at a lower deceleration rate, and then once again at a more rapid deceleration rate. The length of time during which the pacing rate is reduced at the lower deceleration rate is modulated according to the work value maintained by the pacemaker. The work-modulated pacing rate deceleration occurs only if certain achievement criteria are met, the achievement criteria being specified in terms of the amount of time the pacemaker's target pacing rate exceeds a predetermines rest value, and the difference between the target rate and the rest rate.

Title
Rate responsive cardiac pacemaker and method for work-modulating pacing rate deceleration
Application Number
7/880877
Publication Number
5312453
Application Date
May 11, 1992
Publication Date
May 17, 1994
Inventor
Kenneth M Riff
Plymouth
MN, US
Michael R Tollinger
Andover
MN, US
Tommy D Bennett
Shoreview
MN, US
William J Combs
Eden Prairie
MN, US
Michael B Shelton
Minneapolis
MN, US
Agent
Harold R Patton
Reed A Duthler
Assignee
Medtronic
MN, US
IPC
A61N 1/00
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