05302606 is referenced by 120 patents and cites 15 patents.

Methods of inhibiting cell proliferation in a patient suffering from such disorder comprising the use of a styryl-substituted heteroaryl compound wherein the heteroaryl group is a monocyclic ring with 1 or 2 heteroatoms, or a bicyclic ring with 1 to about 4 heteroatoms, said compound optionally substituted or polysubstituted, with the proviso that when said ring is polysubstituted, the substituents do not have a common point of attachment to said ring, and those compounds wherein no substituent on the heteroaryl group is a carboxy group or an ester group, and pharmaceutical compositions comprising such compounds.

Title
Styryl-substituted pyridyl compounds which inhibit EGF receptor tyrosine kinase
Application Number
509942
Publication Number
5302606
Application Date
April 16, 1991
Publication Date
April 12, 1994
Inventor
Chaim Gilon
Jerusalem
IL
Alexander Levitzki
Jerusalem
IL
Paul E Persons
King of Prussia
PA, US
Alfred P Spada
Lansdale
PA, US
Agent
Synnestvedt & Lechner
Assignee
Rhone Poulenc Rorer Pharmaceuticals
PA, US
IPC
A61K 31/44
C07D 213/57
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