05282785 is referenced by 294 patents and cites 64 patents.

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall of the device for direct contact with the passageway wall or body tissue. A further aspect of the present invention involves treating a dilated vessel in the area of a stenotic lesion with a fixative or other drug to render the vessel biologically inert and to form a biological stent or prevent restenosis using specifically selected drugs. A still further aspect of the present invention involves treating a tumor or local or regional tissue mass with antitumor sensitizing agents, biological modifiers, antibiotics or other types of drugs by delivery of the drug to the tumor or tissue area directly or through the passageway wall.

Title
Drug delivery apparatus and method
Application Number
538961
Publication Number
5282785
Application Date
October 5, 1992
Publication Date
February 1, 1994
Inventor
Keith R Hildebrand
Houlton
WI, US
Jin Shimada
Falcon Heights
MN, US
Mark B Knudson
Shoreview
MN, US
James E Shapland
Shoreview
MN, US
Agent
Merchant Gould Smith Edell Welter & Schmidt
Assignee
CorTrak Medical
MN, US
IPC
A61B 17/36
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