05279936 is referenced by 68 patents and cites 5 patents.

Methods are disclosed for separating a component of interest from a mixture containing the component of interest and other components. The method comprises contacting a first liquid medium containing the component of interest and other components with a second liquid medium that is of different density than and/or of different viscosity than the first liquid medium. The contact is carried out in such a way that mixing of the media is minimized or avoided. The component of interest is bound to magnetic particles. The contacted first liquid medium and second liquid medium are subjected to a magnetic field gradient to allow the magnetic particles to migrate into the second liquid medium and separation of the component of interest from other components is realized. Also disclosed are assays employing the present method. Kits for carrying out the present method and assays are also disclosed.

Title
Method of separation employing magnetic particles and second medium
Application Number
7/455550
Publication Number
5279936
Application Date
December 22, 1989
Publication Date
January 18, 1994
Inventor
John Vorpahl
Livermore
CA, US
Agent
Mark L Bosse
Theodore J Leitereg
Assignee
Syntex
CA, US
IPC
G01N 33/537
G01N 33/536
G01N 33/533
G01N 33/543
G01N 33/563
G01N 33/566
G01N 33/53
C12Q 1/00
C12Q 1/68
C12Q 1/70
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