A saliva sampling device includes a holder, a saliva collector and an indicator. The saliva collector selectively receives a sample of saliva. The saliva collector is a piece of filter paper and is fixed to the holder. The indicator is activated by a preselected amount of the received sample of saliva. The indicator is coupled to the holder and to the saliva collector so that a technician can collect the sample of the saliva and determine that it is of adequate amount.